Full list of all 99 The Binding of Isaac achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 52 achievements, and there are 2 DLC packs containing 47 achievements.
Complete Sheol with Eve
Complete the depths without taking damage
Complete the womb without taking damage
100% the game
Complete the caves without taking damage
Make a Super Meat Boy!
stay out of moms things!
Dirty needles... eww
Complete Sheol with ???
Complete the full game with ???
Complete Sheol with Cain
ive lost my head one too many times...
Complete Sheol with Maggy
Complete Sheol with Judas
You defeated Gish!
Complete Sheol with Isaac
Complete the full game 10 times
Complete the full game 9 times
Complete the womb with Eve
Complete the full game 8 times
Complete the full game 7 times
Complete the full game 6 times
Complete the full game 5 times
You defeated Steven!
Complete the full game 4 times
Complete the full game with Cain
Give mom a taste of her own medicine!
Call death upon all of them!
Complete the full game 3 times
mom needs her pills! donate blood.
i lost mine in the arcade...
You defeated C.H.A.D.!
Collect 50+ pennies in one play through
Find Krampus in Satans room for a gift!
Complete the full game 2 times
Complete the full game with Judas
Kids shouldnt play with matches...
Complete the full game
Complete the full game with Maggy
kill mom...
Defeat all bosses in the depths
Destroy the 7 Sins!
Complete the basement without taking damage
Defeat all bosses in the caves
Complete the Caves
Collect 7+ container hearts in one play through
you dont wanna know where this bean has been...
i like to break things...
Defeat all bosses in the basement
Make 2 deals with the devil in one play through
Kids shouldnt play with dead things...
Complete the basement
???
Complete the final chapter with Samson
Complete the final chapter with Judas
Complete the final chapter with Isaac
Complete the final chapter with Eve
Kill Satan with Samson
Complete the final chapter with ???
Complete the final chapter with Cain
Complete the final chapter with Maggy
Complete Challenge 9
Kill moms heart with Samson
Complete Challenge 8
Complete Challenge 2
Complete Challenge 1
Complete Challenge 6
Complete Challenge 5
Complete Challenge 4
Complete Challenge 3
Complete Challenge 7
Kill mom but pass on 2 treasure room items
Beat the game as Cain in Hardmode
Beat the game as Magdalen in Hardmode
Beat the game as Judas in Hardmode
Beat the game as Samson in Hardmode
Beat the game as Eve in Hardmode
Beat the game as ??? in Hardmode, and good luck!
100% the game and hardmode (get all the achievements)
Beat the game as all characters in Hardmode.
Beat Satan in Hardmode
Beat Mom in Hardmode
Beat Moms Heart in Hardmode
Beat the boss in the Cathedral in Hardmode
Beat the Game in Hardmode!
Gain 7 Health upgrades from Eternal Hearts
Beat the game as Isaac in Hardmode