Full list of all 120 Darkest Dungeon achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 69 achievements, and there are 3 DLC packs containing 51 achievements.
Acquire all your Ancestor's Trinkets
Lose a hero to a trap
Kill any boss with a party of four afflicted heroes
Complete a dungeon with all 4 heroes afflicted
Kill all bosses
Complete all Caretaker Goals
Lose a hero to a Maggot
Kill Squiffy Ghast, Swine Skiver, Bone Bearer and Hateful Virago
Fully upgrade the Abbey
Fully upgrade the Town
Kill a Squiffy Ghast with a Jester
Reach week 104
Complete the game on Stygian
Dismas and Reynauld Made it to the final Darkest Dungeon Quest
Lose a hero to hunger
Complete the game with default difficulty options
Complete the game
Complete the game within 99 Weeks
Complete the game on Radiant
Fully upgrade the Tavern
Party wipe on a boss
Lose a hero to Wilbur
Lose all four heroes on a Darkest Dungeon quest
Start a Darkest Dungeon quest with four heroes of resolve level 0
Defeat the brigand Vvulf
Fully upgrade the Blacksmith
Reach week 52
Lose a Legendary (Level 6) hero
Start a quest with all four heroes of Resolve Level 6
Fully upgrade the Guild
Fully upgrade at least four of a hero's skills
Kill the Shrieker
Raise 4 heroes to Resolve Level 6
Slay a Shambler
Fully upgrade a hero's weapons and armor
Slay 1000 enemies
Lock a positive Quirk in the Sanitarium
Raise a hero to Resolve Level 6
Defeat 100 Eldritch enemies
Have one of each class on your roster
Complete 25 quests
Collect at least 20,000 gold from a single quest
Kill any boss with only one hero remaining
Defeat 100 Unholy enemies
Complete a long quest
Complete a quest in all four regions
Walk 500 steps with one hero
Defeat 100 Human enemies
Defeat 100 Beast enemies
Have a character survive 5 attacks at Death's Door in a single combat
Complete 10 quests
Remove a Quirk in the Sanitarium
Kill 50 enemies with one hero
Slay your first boss
Complete a medium quest
Learn a new Camping skill
Collect at least 30 heirlooms from a single quest
Lose a hero to an obstacle
Upgrade a Combat skill
Dismiss your first hero
Treat a hero in the Abbey
Abandon a quest
Lose your first hero to heart attack
First party wipe
Treat a hero in the Tavern
Complete a quest
Lose your first hero
Visit the Graveyard
Reach the Estate
Kill an ally while under the Curse
Defeat the Fanatic
Collect The Invitation
Have your entire roster affected by the crimson curse
Contract the Crimson Curse via contagion
Defeat the Countess
Collect your first Trinket Set
Defeat the Viscount
Build The Red Hook
Defeat the Baron
Lose a hero to Wasting Away from the Curse
Rescue someone
Get infected by the Crimson Curse
Build your first district building
Recruit a flagellant
Collect All of Color of Madness Trinkets
Build the Windmill
Lose a Hero Equipped with the Coat of Many Colors
Lose a Hero Equipped with the Miller's Pipe
Reach Death's Door From Farmhand's Riposte
Earn 200 Shards In One Endless Run
Get 300 Kills
Fight Every Wondering Boss in Endless
Get 200 Kills
Get 100 Kills
Defeat the Sleeper
Defeat the Sleeper With 2 Afflicted, 2 Virtuous Heroes
Gain the Refracted Affliction
Acquire Mildred's Locket Trinket
Use The Shard Dust Provision
All 4 Heroes Dodge the Miller's Reaping
Defeat the Thing From The Stars
Defeat the Miller
Kill the Sleeper's Herald With a Riposte
Complete The First Farmstead Quest
Kill 600 enemies in the Butcher's Circus
Reach the max Prestige level in the Butcher's Circus
Win 100 matches in the Butcher's Circus
Cause 150 heart attacks in the Butcher's Circus
Kill each hero class in the Butcher's Circus
Win any 10 matches without losing any heroes
Win a match in the dueling grounds
Win a match without using any trinkets
Have a single hero survive 4 heart attacks in a single match
Have a hero survive 5 death's door checks in a single match
Daze 10 enemies in the Butcher's Circus
Kill an enemy hero in the first round of a match
Have a single hero deal deathblows to 4 enemies in a single match
Win a match using ONLY stress against your enemies
Cause an enemy hero to have a heart attack
Play your first match in the Butcher's Circus