Full list of all 120 Darkest Dungeon achievements. It takes around 200 hours to unlock all of the achievements in the base game on Windows.
The base game contains 69 achievements, and there are 3 DLC packs containing 51 achievements.
Kill all bosses
Acquire all your Ancestor's Trinkets
Lose a hero to a Maggot
Defeat the brigand Vvulf
Complete a dungeon with all 4 heroes afflicted
Kill any boss with a party of four afflicted heroes
Kill any boss with only one hero remaining
Lose a hero to Wilbur
Lose a hero to an obstacle
Reach week 104
Complete all Caretaker Goals
Kill a Squiffy Ghast with a Jester
Kill the Shrieker
Lose all four heroes on a Darkest Dungeon quest
Start a Darkest Dungeon quest with four heroes of resolve level 0
Lose a hero to a trap
Lose a hero to hunger
Complete the game with default difficulty options
Complete the game
Complete the game within 99 Weeks
Complete the game on Stygian
Complete the game on Radiant
Dismas and Reynauld Made it to the final Darkest Dungeon Quest
Lose a Legendary (Level 6) hero
Reach week 52
Kill Squiffy Ghast, Swine Skiver, Bone Bearer and Hateful Virago
Start a quest with all four heroes of Resolve Level 6
Slay 1000 enemies
Raise 4 heroes to Resolve Level 6
Raise a hero to Resolve Level 6
Fully upgrade a hero's weapons and armor
Fully upgrade at least four of a hero's skills
Complete 25 quests
Walk 500 steps with one hero
Defeat 100 Unholy enemies
Complete a long quest
Slay a Shambler
Fully upgrade the Town
Lock a positive Quirk in the Sanitarium
Fully upgrade the Blacksmith
Fully upgrade the Guild
Fully upgrade the Tavern
Fully upgrade the Abbey
Have one of each class on your roster
Defeat 100 Beast enemies
Defeat 100 Eldritch enemies
Kill 50 enemies with one hero
Have a character survive 5 attacks at Death's Door in a single combat
Learn a new Camping skill
Collect at least 20,000 gold from a single quest
Party wipe on a boss
Defeat 100 Human enemies
Slay your first boss
Complete 10 quests
First party wipe
Lose your first hero to heart attack
Complete a quest in all four regions
Remove a Quirk in the Sanitarium
Treat a hero in the Abbey
Dismiss your first hero
Upgrade a Combat skill
Abandon a quest
Lose your first hero
Complete a medium quest
Treat a hero in the Tavern
Collect at least 30 heirlooms from a single quest
Complete a quest
Visit the Graveyard
Reach the Estate
Defeat the Countess
Kill an ally while under the Curse
Have your entire roster affected by the crimson curse
Defeat the Fanatic
Lose a hero to Wasting Away from the Curse
Build The Red Hook
Defeat the Viscount
Collect your first Trinket Set
Defeat the Baron
Contract the Crimson Curse via contagion
Rescue someone
Collect The Invitation
Build your first district building
Get infected by the Crimson Curse
Recruit a flagellant
Lose a Hero Equipped with the Coat of Many Colors
Lose a Hero Equipped with the Miller's Pipe
Collect All of Color of Madness Trinkets
Reach Death's Door From Farmhand's Riposte
Build the Windmill
Defeat the Sleeper With 2 Afflicted, 2 Virtuous Heroes
Get 300 Kills
Earn 200 Shards In One Endless Run
Fight Every Wondering Boss in Endless
Get 200 Kills
Get 100 Kills
Gain the Refracted Affliction
Defeat the Sleeper
Acquire Mildred's Locket Trinket
Use The Shard Dust Provision
Defeat the Miller
All 4 Heroes Dodge the Miller's Reaping
Kill the Sleeper's Herald With a Riposte
Defeat the Thing From The Stars
Complete The First Farmstead Quest
Win a match in the dueling grounds
Reach the max Prestige level in the Butcher's Circus
Have a single hero survive 4 heart attacks in a single match
Kill 600 enemies in the Butcher's Circus
Kill an enemy hero in the first round of a match
Win 100 matches in the Butcher's Circus
Win a match without using any trinkets
Cause 150 heart attacks in the Butcher's Circus
Kill each hero class in the Butcher's Circus
Win any 10 matches without losing any heroes
Have a hero survive 5 death's door checks in a single match
Win a match using ONLY stress against your enemies
Daze 10 enemies in the Butcher's Circus
Cause an enemy hero to have a heart attack
Have a single hero deal deathblows to 4 enemies in a single match
Play your first match in the Butcher's Circus